A woman is dead and two people are in hospital following a three-vehicle collision in Pictou County, N.S.

The RCMP responded to the crash on Highway 104 in Broadway, N.S. around 4 p.m. Monday.

Police say it appears an SUV was travelling east on the highway when it crossed the centre line and struck the rear driver’s side of an oncoming pickup truck. Investigators say the SUV then collided head-on with a westbound car.

The driver of the car, a 35-year-old Halifax woman, was pronounced dead at the scene.

A three-year-old girl and a four-year-old boy had been in the car with the woman. The boy was taken to hospital with non-life-threatening injuries. The girl wasn’t injured.

The 72-year-old female driver of the SUV sustained serious injuries in the crash and was airlifted to hospital in Halifax. Police say she is from Pomquet, N.S.

The occupants of the truck were not injured.

Highway 104 was closed to traffic in both directions for several hours Monday as police cleared the scene. It has since reopened.

The cause of the crash remains under investigation.